Synthesis of Epibatidine
C11H13ClN2
Principal investigator | Andrew C. Regan |
---|---|
Publication year | 1993 |
Synthesis type | Total |
Number of steps | 7 (3 parts) |
References |
Part 1 of 3
+
H2,
Pd/C
MeCN
RT, 99%
Na(Hg),
Na2HPO4,
NaH2PO4
MeOH, THF
-78 °C to RT
"No yield given."
Part 2 of 3
H2SO4,
HIO4,
I2
AcOH, H2O
80 °C, 53%
Part 3 of 3
+
HBr
AcOH
RT, 22 h, 74%