Synthesis of Gymnomitrol

C15H24O
Principal investigator | Leo A. Paquette |
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Publication year | 1979 |
Synthesis type | Total |
Number of steps | 13 (linear) |
References |
Part 1 of 1
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(CH2OH)2,
TsOH
PhH
Reflux, 95%


"No experimental details were reported for this step."





H2SO4
MeOH
Reflux, 24 h, 74%
"Also isolated was the desired aldol product (22% yield, see the next two steps)."


H2O
AcOH
74%



MeLi
-78 °C, 70%

POCl3
Pyr
Reflux, 2 h, 70%


LiAlH4
THF
0 °C, 45%
