Synthesis of Jamtine
C20H25NO4
| Principal investigator | Nigel S. Simpkins |
|---|---|
| Publication year | 2003 |
| Synthesis type | Total |
| Number of steps | 8 (linear) |
| References |
Part 1 of 1
+
+
AcOH
Reflux
- n-BuLi
- MeO2CCN
AcOH
-78 °C to RT, 3 h, 86%
"99:01 e.r."
NaBH4
EtOH
-5 °C, 89%
(PhSe)2,
KH
THF
50 °C
Pyr,
H2O2
CH2Cl2, H2O
RT, 65% (2 steps)
Me3O+BF4-,
2,6-Di-tert-butyl-4-methylpyridine
CH2Cl2
RT
NaBH4
MeOH
0 °C, 69%