Synthesis of Methoxatin
C14H6N2O8
Principal investigator | Steven M. Weinreb |
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Publication year | 1981 |
Synthesis type | Total |
Number of steps | 14 (linear) |
References |
Part 1 of 1
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- (CH2NMe2)2 , n-BuLi
- CO2
Hexane(s)
RT, 18 h, 66%
- KOH
- HCl
H2O
60% (2 steps)
HNO3
H2SO4
-20 °C, 1.5 min, 60%
NaH
THF
RT, 2 h, 92%
HNO3,
AgO
THF
RT, 10 min, 60%
LiOH
H2O, THF
RT, 5 h, 75%