Synthesis of Decarestrictine D
C10H16O5
Principal investigator | Ronaldo A. Pilli |
---|---|
Publication year | 1998 |
Synthesis type | Total |
Number of steps | 15 (3 parts) |
References |
Part 1 of 3
- NaH
- TBSCl
THF
0 °C, 91%
TBSCl,
Imidazole
DMF
100%
i-Bu2AlH
PhMe
-95 °C
H2SO4,
CrO3
Acetone, H2O
53% (2 steps)
Part 2 of 3
LiAlH4
THF
15 °C to reflux, ON, 85%
TBSCl
83%
Part 3 of 3
+
Pyr.HF
Pyr, THF
HF,
n-Bu4N+ F-
MeCN
80%