Synthesis of Nupharamine
C15H25NO2
Principal investigator | Isao Shimizu |
---|---|
Publication year | 1990 |
Synthesis type | Total |
Number of steps | 9 (linear) |
References |
Part 1 of 1
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Ph3P,
Pd2(dba)3.CHCl3,
HCO2H
Dioxane , Et3N
RT, 8 h, 72%
Pd/C,
H2
Et3N, EtOAc
96%
Ph3P
THF
Reflux, 90%
NaBH4
EtOH
0 °C, 84%
HF
MeOH
73%