Synthesis of Nupharamine
C15H25NO2
| Principal investigator | Jerzy T. Wróbel |
|---|---|
| Publication year | 1977 |
| Synthesis type | Total |
| Number of steps | 7 (linear) |
| References |
Part 1 of 1
+
+
+
AcOH
PhH
RT, 60 min, 35%
LiAlH4
Et2O
Reflux, 3 h, 100%
Zn,
HBr
AcOH, H2O
RT to Reflux, 50 min, 63%
+
NaNH2
Et2O, NH3
-50 to -33 °C, 15 min, 45%
Na
EtOH, Xylene(s)
Reflux, 12%
HCO2H,
HClO4
H2O, MeOH
RT, 40 h, 5%