Synthesis of Cyclophellitol
C7H12O5
Principal investigator | Ken-Ichi Sato |
---|---|
Publication year | 1994 |
Synthesis type | Total |
Number of steps | 13 (linear) |
References |
Part 1 of 1
i-Pr2NLi
CH2Cl2, THF
-78 °C, 82%
NaBH4
DMSO
80 °C, 82%
Ac2O
Pyr
RT, 100%
DBU
4 Å MS
DMSO
80 °C, 60 min, 56% (3 steps)
MsCl,
Et3N
CH2Cl2
0 °C, 86% (2 steps)
TBSCl,
Imidazole
DMF
40 °C, 94%
KOH
EtOH
RT, 20 min, 80%
AcOH
H2O
RT, 60 min, 100%