tert-Butoxy carbamate (Boc)

tert-Butoxy carbamate (Boc) scheme

Protection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • NaH Boc2O
    THF
    50 °C
    22 h
    74 %
    info
    intermediate structure
    NaH, Boc2O
    THF
    50 °C, 22 h, 74%
    intermediate structure

Deprotection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • N/A
    DMSO
    180 °C
    60 min
    69 %
    info
    intermediate structure
    DMSO
    180 °C, 60 min, 69%
    intermediate structure