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Named Reactions
Protecting Groups
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Named Reactions
Protecting Groups
Trifluoroacetamide
Protection :
Reagents
Solvents
Temperature
Time
Yield
Pyr
(CF3CO)2O
CH2Cl2
0 °C - RT
12.5 h
74 %
info
Pyr
,
(CF3CO)2O
CH2Cl2
0 °C to RT, 12.5 h, 74%
K2CO3
(CF3CO)2O
CHCl3
RT
30 min
79 %
info
K2CO3
,
(CF3CO)2O
CHCl3
RT, 30 min, 79%
Deprotection :
Reagents
Solvents
Temperature
Time
Yield
NaOMe
CH2Cl2
MeOH
RT
60 min
82 %
info
NaOMe
CH2Cl2
,
MeOH
RT, 60 min, 82%
K2CO3
H2O
MeOH
Reflux
30 min
100 %
info
K2CO3
H2O
,
MeOH
Reflux, 30 min, 100%