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Named Reactions
Protecting Groups
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Named Reactions
Protecting Groups
Acetamide (Ac)
Protection :
Reagents
Solvents
Temperature
Time
Yield
Ac2O
Pyr
RT - 100 °C
60 min
94-99 %
info
Ac2O
Pyr
100 °C, 60 min, 99%
info
Ac2O
Pyr
RT, 60 min, 94%
Ac2O
N/A
RT
5 min
82%
info
Ac2O
RT, 5 min, 82%
Deprotection :
Reagents
Solvents
Temperature
Time
Yield
KOH
H2O
MeOH
Reflux
6 h
93 %
info
KOH
H2O
,
MeOH
Reflux, 6 h, 93%
HCl
MeOH
Reflux
6 h
58 %
info
HCl
MeOH
Reflux, 6 h, 58%