Thorpe-Ziegler Reaction

Mechanism of the Thorpe-Ziegler Reaction

Original publication	Liebigs Ann.. 1934, 511, 1.
Reviews	Org. React.. 1967, 15, 1. Tetrahedron. 2002, 58, 1.

Sample reactions

KOt-Bu

t-BuOH

85 °C, 2.5 h, 100%