Stobbe Condensation

Schematic representation of the Stobbe Condensation.
Mechanism of the Stobbe Condensation
Mechanism of the Stobbe Condensation
Sample reactions
intermediate structure intermediate structure
NaOMe
MeOH
Reflux, 6 h, 68%
intermediate structure
intermediate structure intermediate structure
KOt-Bu
t-BuOH
Reflux, 22 h, 85%
intermediate structure