Seyferth-Gilbert Homologation

Schematic representation of the Seyferth-Gilbert Homologation.
Mechanism of the Seyferth-Gilbert Homologation
Mechanism of the Seyferth-Gilbert Homologation
Original publication
J. Org. Chem.. 1971, 36, 1379. J. Org. Chem.. 1982, 47, 1837.
Review
Sample reactions
info
intermediate structure
i-Bu2AlH, NaOMe
PhMe, THF
-78 °C to RT, 105 min, 55%
intermediate structure