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Named Reactions
Protecting Groups
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Named Reactions
Protecting Groups
Sandmeyer Reaction
Mechanism of the Sandmeyer Reaction
Original publication
Ber. Dtsch. Chem. Ges.. 1884, 17, 1633.
Review
Chem. Rev.. 1947, 40, 251.
Sample reactions
info
CuBr
,
H2SO4
,
HBr
,
NaNO2
AcOH
,
H2O
0 to 80 °C, 14 h, 92%
info
H2SO4
,
KI
,
NaNO2
H2O
,
MeCN
0 °C to RT, 15 min
info
HCl
,
NaNO2
H2O
0 °C to RT, , 74%
info
110-120 °C, 2 h, 60% (2 steps)