Pomeranz-Fritsch Isoquinoline Synthesis

Schematic representation of the Pomeranz-Fritsch Isoquinoline Synthesis.
Mechanism of the Pomeranz-Fritsch Isoquinoline Synthesis
Mechanism of the Pomeranz-Fritsch Isoquinoline Synthesis
Original publication
Monatsh. Chem.. 1893, 14, 116. Ber. Dtsch. Chem. Ges.. 1893, 26, 419.
Reviews
Heterocycles. 1987, 25, 601. Org. React.. 1951, 6, 191.
Sample reactions
info
intermediate structure
H2SO4
H2O
0 °C to RT, 48 h, 64%
intermediate structure