Norrish Reaction

Schematic representation of the Norrish Reaction.

Mechanism of the Norrish Reaction

Mechanism of the Norrish Reaction

Original publication	Nature. 1936, 138, 1016. Nature. 1937, 140, 195. Tetrahedron Lett.. 2010, 51, 872.
Reviews	Acc. Chem. Res.. 1971, 4, 168. Rev. Chem. Intermed.. 1978, 2, 139.

Sample reactions

intermediate structure

Et3N

hν

PhH, t-BuOH

RT, 18 h, 90%

intermediate structure

intermediate structure

hν

MeOH, PhMe

-78 °C to RT, 18 h, 36%

intermediate structure

intermediate structure

Et3N

hν

PhH, t-BuOH

RT, 10 h, 100%

intermediate structure

intermediate structure

hν

MeOH

RT, 30 min

intermediate structure

intermediate structure

hν

Cyclohexane

RT, 14 h, 40%

intermediate structure

intermediate structure

hv

PhH

RT, 9.5 h, 37% (50% BRSM)

intermediate structure