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Named Reactions
Protecting Groups
Hofmann-Löffler-Freytag Reaction
Mechanism of the Hofmann-Löffler-Freytag Reaction
Original publication
Ber. Dtsch. Chem. Ges.. 1883, 16, 558.
Ber. Dtsch. Chem. Ges.. 1909, 42, 3427.
Tetrahedron. 1982, 40, 355.
Reviews
Angew. Chem. Int. Ed.. 1983, 22, 337.
Chem. Rev.. 1963, 63, 55.
Tetrahedron. 1995, 51, 7095.
Sample reactions
info
NaOEt
EtOH
Reflux, 10 min, 88%
info
hν
CF3CO2H
0 °C, 50 min