Sample reactions
intermediate structure
AcOH, CH2O, Me2NH
Dioxane , H2O
RT, 2 h, 92%
intermediate structure
intermediate structure intermediate structure
HCl
EtOH, H2O
Reflux, 60 min, 55%
intermediate structure
intermediate structure
NaH, PrenylBr
PhMe
35 °C, 19 h, 73%
intermediate structure
intermediate structure
Sc(OTf)3
DCE, H2O
120 °C, 36 h, 73%
intermediate structure
intermediate structure
TsOH
PhMe
RT, 16 h, 55% (2 steps)
intermediate structure
intermediate structure
Br2
CH2Cl2
-78 °C to RT, 4 h, 81%
intermediate structure
intermediate structure
Br2
CH2Cl2
-78 °C to RT, 4 h, 53%
intermediate structure
intermediate structure
AgOTf, DBU, 2,6-Di-tert-butyl-4-methylpyridine
PhMe
RT, 13.5 h, 70%
intermediate structure
intermediate structure
H2SO4
90 °C, 4 h
intermediate structure intermediate structure
intermediate structure
H3PO4
Xylene(s)
Reflux, 2 h, 91%
intermediate structure
intermediate structure
AlBr3
PhH
40 °C to Reflux, 42 h, 80%
intermediate structure
intermediate structure
H3PO4
Xylene(s)
Reflux, ON, 92%
intermediate structure
intermediate structure
AlBr3
PhH
RT to 50 °C, 7 d, 88% (2 steps)
intermediate structure
intermediate structure
AlBr3
PhH
RT, 3-5 d, 57% (2 steps)
intermediate structure
intermediate structure
PPA
120 °C, 12-60 h, 91%
intermediate structure
intermediate structure
H3PO4
Xylene(s)
Reflux, 25-30 h, 40% (2 steps)
intermediate structure
intermediate structure
H3PO4
Xylene(s)
Reflux, 5-8 h, 33%
intermediate structure
intermediate structure
AlBr3
PhH
RT, 3 d, 40%
intermediate structure
intermediate structure
H2SO4
Acetone, H2O
0 °C, 2 h, 80%
intermediate structure
intermediate structure intermediate structure
SnCl4
CH2Cl2
RT, 30 min, 98%
intermediate structure