Evans-Saksena Reduction

Schematic representation of the Evans-Saksena Reduction.
Mechanism of the Evans-Saksena Reduction
Mechanism of the Evans-Saksena Reduction
Sample reactions
intermediate structure
AcOH, Me4N+ BH(OAc)3-
MeCN
-40 to -20 °C, 3 d, 99%
intermediate structure
intermediate structure
Me4N+ BH(OAc)3-
AcOH, MeCN
0 °C, 24 h, 90%
intermediate structure