Eschenmoser-Claisen Rearrangement

Mechanism of the Eschenmoser-Claisen Rearrangement

Original publication	Helv. Chim. Acta. 1964, 47, 2425.
Reviews	Comp. Org. Syn.. 1991, 5, 827. Chem. Rev.. 2004, 104, 293. Chem. Rev.. 1988, 88, 1423.

Sample reactions

CH(OMe)2NMe2

Decalin

250 °C, 2 h, 44%