Duff Reaction

Schematic representation of the Duff Reaction.
Mechanism of the Duff Reaction
Mechanism of the Duff Reaction
Original publication
J. Chem. Soc.. 1932, 0, 1987. Synthesis. 1999, 1999, 1878. Synthesis. 1999, 1999, 1878.
Review
Sample reactions
info
intermediate structure
HMTA
AcOH
110 °C, 48 h, 40%
intermediate structure
info
intermediate structure
HMTA
CF3CO2H
Reflux, 12 h, 39%
intermediate structure