De Mayo Reaction

Schematic representation of the De Mayo Reaction.
Mechanism of the De Mayo Reaction
Mechanism of the De Mayo Reaction
Original publication
Proc. Chem. Soc.. 1962, 0, 119.
Reviews
Acc. Chem. Res.. 1971, 4, 41. Org. React.. 1993, 44, 297.
Sample reactions
info
intermediate structure
hν
Acetone, MeCN
0 °C, 16 h, 60%
intermediate structure intermediate structure
info
intermediate structure intermediate structure
K2CO3
MeOH
RT, 36 h
intermediate structure intermediate structure
info
intermediate structure
hν
Cyclohexane
15-30 °C, , 83%
intermediate structure
info
intermediate structure
H2, Pd/C
3 atm
AcOH
RT, 18 h, 83%
intermediate structure
info
intermediate structure intermediate structure
hν
MeOH
RT, 5 d
intermediate structure intermediate structure