Chugaev Elimination

Mechanism of the Chugaev Elimination

Original publication	Ber. Dtsch. Chem. Ges.. 1900, 33, 3118.
Reviews	Chem. Rev.. 1960, 60, 431. Org. React.. 1962, 12, 57.

Sample reactions

DME

170 °C, 5 h, 74%

"Overall yield after the recovered starting material was resubmitted to the same conditions."

200 °C, , 100%

24 mmHg

180 °C, 60 min, 99%