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Bradsher Cyclization

Schematic representation of the Bradsher Cyclization.

Mechanism of the Bradsher Cyclization

Mechanism of the Bradsher Cyclization

Original publication	J. Am. Chem. Soc.. 1940, 62, 486.
Review	Chem. Rev.. 1987, 87, 1277.

Sample reactions

intermediate structure

SnCl4

CH2Cl2

0 °C to RT, 7 h, 66%

intermediate structure

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