Baeyer-Villiger Oxidation

Mechanism of the Baeyer-Villiger Oxidation

Sample reactions

mCPBA
CH2Cl2
95%


H2O2, NaOH
H2O, MeOH
RT, 2.5 h, 42%
"The product was selectively cristallized from the resulting mixture of isomers."


AcOOH, NaOAc
AcOH, H2O
RT to 80 °C, 16 h, 85% (2 steps)


NaOH, Ph3COOH
Acetone, H2O
-30 °C, 2 h, 86%


H2O2 (Urea complex), (CF3CO)2O
CH2Cl2
RT, 45 h, 63%


mCPBA
CH2Cl2
RT, 16 h


mCPBA
CH2Cl2


mCPBA, CF3CO2H
CH2Cl2
5 °C, 16 h, 87%


mCPBA, Na2HPO4
CH2Cl2
RT, 15 h, 61%


mCPBA
CH2Cl2
RT, , 90%
