Synthesis of Hirsutene

Structure of Hirsutene

C15H24

Principal investigatorRaymond L. Funk
Publication year1984
Synthesis typeFormal
Number of steps 8 (linear)
References
Part 1 of 1
intermediate structure + intermediate structure
TiCl4
CH2Cl2
71%
intermediate structure
MeNHOH.HCl, NaOEt
PhMe, EtOH
Reflux, 24-36 h, 75%
intermediate structure
MeI
intermediate structure
H2, Pd
89% (2 steps)
intermediate structure
mCPBA, NaHCO3
CH2Cl2, H2O
50 °C, 48 h, 90%
intermediate structure
HCrO3Cl.Pyr
intermediate structure
H2, Pd
65% (2 steps)
intermediate structure
Remaining...
70% (1 step)
"See: Tetrahedron Lett. 1976, 17, 195."
intermediate structure