tert-Butoxy carbamate (Boc)

tert-Butoxy carbamate (Boc) scheme

Protection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • Boc2O DMAP
    CH2Cl2
    RT
    20 min
    100 %
    intermediate structure
    Boc2O, DMAP
    CH2Cl2
    RT, 20 min, 100%
    intermediate structure

Deprotection :

  • Reagents
    Solvents
    Temperature
    Time
    Yield
  • CF3CO2H Me2S
    CH2Cl2
    RT
    30 min
    97 %
    intermediate structure
    Me2S
    CF3CO2H, CH2Cl2
    RT, 30 min, 97%
    intermediate structure