Browse by molecules
Browse by principal investigator
Browse by date
Browse by carbon count
menu
Browse Syntheses
arrow_drop_down
Named Reactions
Protecting Groups
Browse Syntheses
arrow_drop_down
Browse by molecules
Browse by principal investigator
Browse by date
Browse by carbon count
Named Reactions
Protecting Groups
tert-Butoxy carbamate (Boc)
Protection :
Reagents
Solvents
Temperature
Time
Yield
Et3N
Boc2O
CH2Cl2
RT
60 min
100 %
info
Et3N
,
Boc2O
CH2Cl2
RT, 60 min, 100%
NaHCO3
Boc2O
EtOAc
H2O
RT
3 h
91 %
info
NaHCO3
,
Boc2O
EtOAc
,
H2O
RT, 3 h, 91%
Deprotection :
Reagents
Solvents
Temperature
Time
Yield
CF3CO2H
CH2Cl2
0 °C - RT
20 min - 6 h
65-91 %
info
CF3CO2H
CH2Cl2
RT, 20 min, 83%
info
CF3CO2H
CH2Cl2
RT, 6 h, 65%
info
CF3CO2H
CH2Cl2
RT, 60 min, 91%
info
CF3CO2H
CH2Cl2
RT, 5 h, 89%
info
CF3CO2H
CH2Cl2
0 °C to RT, 30 min, 90%
Et3N
TMSOTf
CH2Cl2
0 °C - RT
60 min
97 %
info
Et3N
,
TMSOTf
CH2Cl2
0 °C to RT, 60 min, 97%
AcCl
EtOH
RT
16 h
100 %
info
AcCl
EtOH
RT, ON, 100%