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Named Reactions
Protecting Groups
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Named Reactions
Protecting Groups
Trimethylsilyl cyanohydrin
Protection :
Reagents
Solvents
Temperature
Time
Yield
TMSCN
ZnI2
PhH
RT
18 h
96 %
info
TMSCN
,
ZnI2
PhH
RT, 18 h, 96%
KCN
18-Crown-6
TMSCN
CH2Cl2
0 °C - RT
8 h
89 %
info
KCN
,
18-Crown-6
,
TMSCN
CH2Cl2
0 °C to RT, 8 h, 89%
Deprotection :
Reagents
Solvents
Temperature
Time
Yield
n-Bu4N+ F-
THF
-78 °C
15 min
80 %
info
n-Bu4N+ F-
THF
-78 °C, 15 min, 80%