Protecting groups
Select a protective group to get the conditions needed to install/remove the group. Several reaction samples of protection and deprotection are shown for each groups.
All of theses reactions are taken from our synthesis database and the list is continually growing.
Protection of Alcohol
2,2,2-Trichloroethyl carbonate (Troc)
2-Methoxyethoxymethyl ether (MEM)
2-Naphthylmethyl ether (Nap)
4-Methoxybenzyl ether (PMB)
Acetate (Ac)
Benzoate (Bz)
Benzyl ether (Bn)
Benzyloxymethyl acetal (BOM)
Ethoxyethyl acetal (EE)
Methoxymethyl acetal (MOM)
Methoxypropyl acetal (MOP)
Methyl ether
Tetrahydropyranyl acetal (THP)
Triethylsilyl ether (TES)
Triisopropylsilyl ether (TIPS)
Trimethylsilyl ether (TMS)
tert-Butyldimethylsilyl ether (TBS, TBDMS)
tert-Butyldiphenylsilyl ether (TBDPS)