Steglich Esterification

Schematic representation of the Steglich Esterification.
Mechanism of the Steglich Esterification
Mechanism of the Steglich Esterification
Original publication
Review
Sample reactions
intermediate structure
DCC, Cl3CCH2OH
CH2Cl2, Pyr
intermediate structure
intermediate structure
DCC
Pyr
100 °C, 2 h, 67%
intermediate structure
intermediate structure intermediate structure
DCC, DMAP
CH2Cl2
36 h, 82%
intermediate structure
intermediate structure intermediate structure
DCC, DMAP
CH2Cl2
-20 °C, 20 h, 98%
intermediate structure
intermediate structure intermediate structure
DCC, DMAP
CH2Cl2
RT, 40 h, 86%
intermediate structure