Pomeranz-Fritsch Isoquinoline Synthesis

Mechanism of the Pomeranz-Fritsch Isoquinoline Synthesis

Original publication	Monatsh. Chem.. 1893, 14, 116. Ber. Dtsch. Chem. Ges.. 1893, 26, 419. Bull. Chem. Soc. Jpn.. 2005, 78, 180.
Reviews	Heterocycles. 1987, 25, 601. Org. React.. 1951, 6, 191.

Sample reactions

H2SO4

H2O

0 °C to RT, 48 h, 64%