Browse by molecules
Browse by principal investigator
Browse by date
Browse by carbon count
menu
Browse Syntheses
arrow_drop_down
Named Reactions
Protecting Groups
Browse Syntheses
arrow_drop_down
Browse by molecules
Browse by principal investigator
Browse by date
Browse by carbon count
Named Reactions
Protecting Groups
Pinacol Coupling
Mechanism of the Pinacol Coupling
Original publication
Liebigs Ann.. 1859, 110, 23.
Reviews
Angew. Chem. Int. Ed.. 1996, 35, 61.
Comp. Org. Syn.. 1991, 3, 563.
Top. Curr. Chem.. 2007, 279, 53.
Sample reactions
info
Zn-Cu
,
(TiCl3)2.2DME
DME
70 °C, 60 min, 23%
info
LiAlH4
,
TiCl2
THF
0 °C to Reflux, 40 min, 43-71%
info
Na
NH3
-33 °C, , 80%
info
SmI2
THF
Reflux, 2.5 h, 78%