Sample reactions
intermediate structure
PhSCHLiTMS
THF
-23 to 0 °C, 4 h, 64% (2 steps)
intermediate structure
intermediate structure
TMSCHBrCO2Et, i-Pr2NLi
THF
-78 °C, , 70%
intermediate structure
intermediate structure
TMSCH2CN, n-BuLi, B(Oi-Pr)3
THF
-78 °C, 90 min, 67%
"Also isolated was the E-isomer (12 % yield)."
intermediate structure
intermediate structure intermediate structure
n-BuLi
THF
-15 °C
intermediate structure