Meerwein-Ponndorf-Verley Reduction

Schematic representation of the Meerwein-Ponndorf-Verley Reduction.
Mechanism of the Meerwein-Ponndorf-Verley Reduction
Mechanism of the Meerwein-Ponndorf-Verley Reduction
Sample reactions
intermediate structure
Al, NaOEt
EtOH
Reflux, 2 h, 5%
"(-)-Quinine was selectively cristallized (as a tartrate salt) from the resulting four diastereoisomers."
intermediate structure
intermediate structure
Al(Oi-Pr)3
i-PrOH
Reflux, 60 min, 60%
intermediate structure