Madelung Indole Synthesis

Schematic representation of the Madelung Indole Synthesis.
Mechanism of the Madelung Indole Synthesis
Mechanism of the Madelung Indole Synthesis
Original publication
Ber. Dtsch. Chem. Ges.. 1912, 45, 1128.
Review
Sample reactions
info
intermediate structure intermediate structure
n-BuLi, TMSCl, s-BuLi
Et2O, THF
-78 to 0 °C, 2 h, 62%
intermediate structure