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Named Reactions
Protecting Groups
Itsuno-Corey Reduction
Mechanism of the Itsuno-Corey Reduction
Original publication
J. Chem. Soc., Chem. Commun.. 1981, 7, 315.
J. Am. Chem. Soc.. 1987, 109, 5551.
J. Am. Chem. Soc.. 2013, 135, 3307.
Reviews
Angew. Chem. Int. Ed.. 1998, 37, 1986.
Tetrahedron. 2006, 62, 7621.
Sample reactions
info
CBS Reagent
THF
RT, 6 h, 88%
info
CBS Reagent
CH2Cl2
,
PhMe
-78 °C, 5.5 d, 84%
info
CBS Reagent
,
Catecholborane
CH2Cl2
-78 °C, 10 h, 94%
info
CBS Reagent
,
Catecholborane
93%
info
CBS Reagent
,
BH3.Me2S
THF
-30 °C, 10 min, 75%
">99:01 e.r."